Research

Publications

Haring E, Andrieux G, Uhl FM, Krausz M, Prioretti M, …, Börries M, Aumann K, Zeiser R, Apostolova P. Therapeutic targeting of endoplasmic reticulum stress in acute graft- versus-host disease. Haematologica (2022). Gorski M, Rasheed H, Teumer A, Thomas LF, Graham SE, .., Köttgen M, …, Köttgen A, Kronenberg F, Heid IM. Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies. Kidney Int (2022). Bernhard P, Bretthauer BA, Brixius SJ, Bügener H, Groh JE, …, Beyersdorf F, Schilling O, Pooth JS. Serum proteome alterations during conventional and extracorporeal resuscitation in pigs. J Transl Med (2022). Hölzen L, Mitschke J, Schönichen C, Hess ME, Ehrenfeld S, Börries M, Miething C, Brummer T, Reinheckel T. RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells. Theranostics (2022). Fröhlich K, Brombacher E, Fahrner M, Vogele D, Kook L, …, Bärenfaller K, Kreutz C, Schilling O. Benchmarking of analysis strategies for data-independent acquisition proteomics using a large-scale dataset comprising inter-patient heterogeneity. Nat Commun (2022). Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, …, Wuttke M, …, Preissl S, …, Köttgen A, …, Rotter JI, McCarthy MI, Morris AP. Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Nat Genet (2022). Keshawarz A, Hwang SJ, Lee GY, Yu Z, Yao C, Köttgen A, Levy D. Cardiovascular disease protein biomarkers are associated with kidney function: The Framingham Heart Study. PLoS One (2022). Steinbrenner I, Sekula P, Kotsis F, von Cube M, Cheng Y, …, Eckardt KU, Schultheiss UT, GCKD investigators. Association of osteopontin with kidney function and kidney failure in chronic kidney disease patients: the GCKD study. Nephrol Dial Transplant (2022). Kumar P, Zadjali F, Yao Y, Köttgen M, Hofherr A, Gross KW, Mehta D, Bissler JJ. Single Gene Mutations in Pkd1 or Tsc2 Alter Extracellular Vesicle Production and Trafficking. Biology (Basel)(2022). Pinter N, Glätzer D, Fahrner M, Fröhlich K, Johnson J, …, Drepper F, Schilling O, Föll MC. MaxQuant and MSstats in Galaxy Enable Reproducible Cloud-Based Analysis of Quantitative Proteomics Experiments for Everyone. J Proteome Res (2022). Aypek H, Krisp C, Lu S, Liu S, Kylies D, …, Bergmann C, Huber TB, Grahammer F. Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy. J Clin Invest (2022). Münch J, Engesser M, Schönauer R, Hamm JA, Hartig C, …, Bergmann C, …, Lo CW, Popp B, Halbritter J. Biallelic pathogenic variants in roundabout guidance receptor 1 associate with syndromic congenital anomalies of the kidney and urinary tract. Kidney Int (2022). Chen TK, Surapaneni AL, Arking DE, Ballantyne CM, Boerwinkle E, …, Köttgen A, Susztak K, Tin A, Yu B, Grams ME. APOL1 Kidney Risk Variants and Proteomics. Clin J Am Soc Nephrol (2022). Zhang J, Dutta D, Köttgen A, Tin A, Schlosser P, …, Boerwinkle E, Coresh J, Chatterjee N. Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies. Nat Genet (2022). Li Y, Cheng Y, Consolato F, Schiano G, Chong MR, …, Sekula P, Steinbrenner I, Schlosser P, …, Schultheiss UT, …, Wuttke M, …, Devuyst O, Rampoldi L, Köttgen A. Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases. JCI Insight (2022). KDIGO Conference Participants. Genetics in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int (2022).