Müller M, Zodel K, Abhari BA, Cuomo F, Nizamuddin S, Metzger P, Boerries M, Timmers HTM, Frew IJ. KDM5C and KDM5D mutations have different consequences in clear cell renal cell carcinoma cells. Commun Biol (2025).
Pal J, Riester M, Ganner A, …, Frew IJ, Kotsis F, Neumann-Haefelin E, Spang A, Diederichs S. Nonstop mutations cause loss of renal tumor suppressor proteins VHL and BAP1 and affect multiple stages of protein translation. Sci Adv (2025).
Felixberger PT, Andrieux G, Maul-Pavicic A, …, Boerries M, Nitschke L, Voll RE, Warnatz K, Keller B. CD21low B cells reveal a unique glycosylation pattern with hypersialylation and hyperfucosylation. Front Immunol (2025).
Schumann A, Garbade SF, Beblo S, …, Thimm E, Weinhold N, Williams M, Wortmann S, Grünert SC. Kidney involvement in glycogen storage disease type I: Current knowledge and key challenges. Mol Genet Metab (2025).
Braun LM, Giesler S, Andrieux G, …, Boerries M, …, Schell C, …, Becher B, Funke-Lorenz C, Placke JM, Apostolava P, Zeiser R. Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity. Cancer Cell (2025).
Li MJ, Meyer LC, Meier N, Wittke J, Maldacker M, Seredynska A, Schueler J, Schilling O, Föll MC. Spatial Proteomics by Parallel Accumulation-Serial Fragmentation Supported MALDI MS/MS Imaging: A First Glance Into Multiplexed and Spatial Peptide Identification. Rapid Commun Mass Spectrom (2025).
Brombacher E, Schilling O, Kreutz C. Characterizing the omics landscape based on 10,000+ datasets. Sci Rep (2025).
Scherer N, Fässler D, Borisov O, Cheng Y, Schlosser P, Wuttke M, …, Sekula P, Hoppmann A, Schultheiss UT, …, Schmidts, Köttgen M, …, Grünert SC, Estrada K, Thiele I, Hertel J, Köttgen A. Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits. Nat Genet (2025).
Catalano A, Haas LS, Zodel K, …, Haug S, Köttgen A, Köhler N, Boerries M, Frew I. Mutations in tumor suppressor genes Vhl and Rassf1a cause DNA damage, chromosomal instability and induce gene expression changes characteristic of clear cell renal cell carcinoma. Kidney Int (2024).
Butz E, Schultheiss UT, Sekula P. Modeling heterogeneity in the progression of chronic kidney disease. Nephrol Dial Transplant (2024).
Schumann A, Martinez-Pizarro A, Richard E, Schell C, …, Schilling O, Barry M, Neubauer B, Köttgen M, Hannibal L, Desivat LR, Spiekerkötter U. Renal phenotyping in a hypomorphic murine model of propionic aciduria reveals common pathomechanisms in organic acidurias. Sci Rep (2024).
Lempicki C, Milosavljevic J, Laggner C, Tealdi S, Meyer C, Walz G, Lang K, Campa CC, Hermle T. Discovery of a Small Molecule with an Inhibitory Role for RAB11. Int J Mol Sci (2024).
Schröder CM, Zissel L, Mersiowsky SL, …, Schüle KM, Preissl S, Schilling O, Timmers M, Arnold S. EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling. Dev Cell (2024).
Wang Y, Hess ME, Tan Y, Esser PR, Nyström A, Boerries M, Sayar SB, Has C. Alterations in the microenvironment of junctional epidermolysis bullosa keratinocytes: A gene expression study. Matrix Biol (2024).
Dinh TLJ, Rogg M, Cosenza-Contreras M, …, Werner M, Grabbert M, Bronsert P, Schell C, Schilling O. Proteomic analysis of non-muscle invasive and muscle invasive bladder cancer highlights distinct subgroups with metabolic, matrisomal, and immune hallmarks and emphasizes importance of the stromal compartment. J Pathol (2024).
Busch T, Neubauer B, Schmitt L, …, Hofherr A, Schell C, Schilling O, Westermann L, Köttgen M. The role of the co-chaperone DNAJB11 in polycystic kidney disease: Molecular mechanisms and cellular origin of cyst formation. FASEB J (2024).
