Catalano A, Haas LS, Zodel K, …, Haug S, Köttgen A, Köhler N, Boerries M, Frew I. Mutations in tumor suppressor genes Vhl and Rassf1a cause DNA damage, chromosomal instability and induce gene expression changes characteristic of clear cell renal cell carcinoma. Kidney Int (2024).
Butz E, Schultheiss UT, Sekula P. Modeling heterogeneity in the progression of chronic kidney disease. Nephrol Dial Transplant (2024).
Schumann A, Martinez-Pizarro A, Richard E, Schell C, …, Schilling O, Barry M, Neubauer B, Köttgen M, Hannibal L, Desivat LR, Spiekerkötter U. Renal phenotyping in a hypomorphic murine model of propionic aciduria reveals common pathomechanisms in organic acidurias. Sci Rep (2024).
Lempicki C, Milosavljevic J, Laggner C, Tealdi S, Meyer C, Walz G, Lang K, Campa CC, Hermle T. Discovery of a Small Molecule with an Inhibitory Role for RAB11. Int J Mol Sci (2024).
Schröder CM, Zissel L, Mersiowsky SL, …, Schüle KM, Preissl S, Schilling O, Timmers M, Arnold S. EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling. Dev Cell (2024).
Wang Y, Hess ME, Tan Y, Esser PR, Nyström A, Boerries M, Sayar SB, Has C. Alterations in the microenvironment of junctional epidermolysis bullosa keratinocytes: A gene expression study. Matrix Biol (2024).
Dinh TLJ, Rogg M, Cosenza-Contreras M, …, Werner M, Grabbert M, Bronsert P, Schell C, Schilling O. Proteomic analysis of non-muscle invasive and muscle invasive bladder cancer highlights distinct subgroups with metabolic, matrisomal, and immune hallmarks and emphasizes importance of the stromal compartment. J Pathol (2024).
Busch T, Neubauer B, Schmitt L, …, Hofherr A, Schell C, Schilling O, Westermann L, Köttgen M. The role of the co-chaperone DNAJB11 in polycystic kidney disease: Molecular mechanisms and cellular origin of cyst formation. FASEB J (2024).
Gruber I, Kollerits B, Forer L, …, Schultheiss UT, Köttgen A, Eckardt KU, Coassin S, Lamina C, Kronenberg F. Lipoprotein(a) concentrations and cardiovascular disease in patients with chronic kidney disease: Results from the German Chronic Kidney Disease study. J Intern Med (2024).
Ferrarese R, Joseph K, Andrieux G, …, Prinz M, Ravi VM, Boerries M, Heiland DH, Carro MS. ZBTB18 regulates cytokine expression and affects microglia/macrophage recruitment and commitment in glioblastoma. Commun Biol (2024).
Vogele D, Wöhrle S, Saller BS, Fröhlich K, Barta BA, Cosenza-Contreras M, Groß O, Schilling O. Size exclusion chromatography based proteomic and degradomic profiling of inflammasome-activated, murine bone marrow-derived dendritic cells highlights complex retention and release of cleavage products. Mol Omics (2024).
Salié H, Wischer L, D’Alessio A, …, Boerries M, …, Hofmann M, Thimme R, Pinato DJ, Longerich T, Bengsch B. Spatial single-cell profiling and neighbourhood analysis reveal the determinants of immune architecture connected to checkpoint inhibitor therapy outcome in hepatocellular carcinoma. Gut (2024).
Eble J, Köttgen A, Schultheiss UT. Monogenic Kidney Diseases in Adults With Chronic Kidney Disease (CKD). Dtsch Arztebl Int (2024).
Dannenberg F, von Moers A, Bittigau P, …, Broekema MF, Schuelke M, Kaindl AM, Scholl U, Ortner NJ. A Novel De Novo Gain-of-Function CACNA1D Variant in Neurodevelopmental Disease With Congenital Tremor, Seizures, and Hypotonia. Neurol Genet (2024).
Grahammer F, Dumoulin B, Gulieva RE, Arnold F, …, Freedman BS, Busch H, Boerries M, Walz G, Huber TB. Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity. Kidney Int (2024).
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