Projects

Research Projects

Genetic and epigenetic dysregulation in congenital anomalies of the kidneys and urinary tract

Miriam Schmidts

Discovery and characterization of new genes/proteins in cystic kidney disease and related ciliopathies

Carsten Bergmann
Elisabeth Ott

Elucidating the function of NPHP gene products and compensatory mechanisms in nephronophthisis and related ciliopathies

Toma Yakulov
Peter Walentek

Applying the Concept of Synthetic Lethality to the Treatment of Autosomal Dominant Polycystic Kidney Disease

Michael Köttgen

The role of endosomal regulators for slit diaphragm formation and maintenance

Tobias Hermle

High-resolution proteomic analysis of native sodium-phosphate transporters SLC34A1 and SLC34A3 and their role in kidney disease

Bernd Fakler

Structure and function of disease-relevant renal transport proteins

Carola Hunte

VHL-dependent licensing of hetero-cellular crosstalks within the tumor micro-environment of clear cell renal cell carcinoma (ccRCC)

Oliver Schilling
Christoph Schell

Deregulation of mTOR signaling pathways and metabolic reprogramming in VHL-dependent clear cell renal cell carcinoma

Elke Neumann-Haefelin
Pascal Schlosser

The role of MIF in the development and progression of renal carcinoma

Ian Frew

Target identification across the allele frequency spectrum: from complex to monogenic kidney disease

Matthias Wuttke
Ulla T. Schultheiß

Discovery and characterization of genes with cell-type and compartment-specific functions in the kidney and their role in disease

Anna Köttgen

Gene regulatory programs in autosomal dominant polycystic kidney disease

Michael Köttgen
Sebastian Preissl

Understanding differential disease manifestations of VHL mutations via the plurality of their molecular functions

Sven Diederichs
Athina Ganner

Hereditary lysosomal storage and metabolic diseases in the kidney

Tobias Huber
Anke Schumann

Deciphering the mechanistic role of formin DAAM2 in genetic podocytopathies

Robert Grosse
Tobias Hermle

Service Projects

Planning, integrative analyses and modeling of high-dimensional data

Melanie Börries
Anna Köttgen

Information Infrastructure Project for Research Data Management

Harald Binder