Projects

Research Projects

Trafficking defects in reno-skeletal ciliopathies

Ekkehart Lausch
Miriam Schmidts

Characterization of new genes encoding putative transition zone proteins in cystic kidney disease and ciliopathies

Carsten Bergmann
Elisabeth Ott

The role of nephronophthisis proteins (NPHPs) in organelle, cell and tissue organization

Gerd Walz
Toma Yakulov

Investigating alternative splicing and isoform functions in ciliopathy- and renal disease-genes

Peter Walentek

Analysis of the polycystin-1 signaling module to identify disease modifiers and therapeutic targets for polycystic kidney disease

Michael Köttgen

The role of endosomal regulators for slit diaphragm formation and maintenance

Tobias Hermle

Control of kidney morphogenesis by CAKUT- and kidney function-associated transcription factors

Sebastian Arnold

Primary aldosteronism – genetics, pathophysiology and role in hypertensive kidney disease

Ute Scholl

High-resolution proteomic analysis of native sodium-phosphate transporters SLC34A1 and SLC34A3 and their role in kidney disease

Bernd Fakler

Structure, function and regulation of disease-relevant renal transport proteins

Carola Hunte

Matrisome composition and processing in renal tumors of VHL disease

Oliver Schilling
Christoph Schell

Rebalancing epigenetic and mTOR signaling in VHL-dependent clear cell renal cell carcinoma

Marc Timmers
Elke Neumann-Haefelin

Interplay between genetic and microenvironmental factors in the development of renal carcinoma

Ian Frew

Target identification across the allele frequency spectrum: from complex to monogenic kidney disease

Matthias Wuttke

Discovery and integrated functional genomics of cell-type and compartment-specific kidney disease genes

Anna Köttgen

Service Projects

Planning, integrative analyses and modeling of high-dimensional data

Melanie Börries
Anna Köttgen
Harald Binder

Information Infrastructure Project for Research Data Management

Harald Binder