Peggy Sekula

PD Dr.
Principal Investigator
(Associated Member)

Institute of Genetic Epidemiology
Medical Center – University of Freiburg
Hugstetter Str. 49
79106 Freiburg

Current Position

Senior Researcher / Statistician

Academic Education

1999 - 2003 Diploma in Mathematics (Dipl-Math (FH)), Berlin

Advanced Qualifications

2020 Habilitation (PD), Faculty of Medicine, University of Freiburg
2012 Doctoral degree in Mathematics (Dr. rer. nat.)
Faculty of Mathematics and Physics, University of Freiburg

Postgraduate Positions

2012 - present Medical Center – University of Freiburg, Institute of Genetic Epidemiology

Publications on CRC 1453 funding

Yeo WJ, Surapaneni AL, Hasson DC, Schmidt IM, Sekula PKöttgen A, …, Vasan RS, Kimmel PL, Coresh J, Grams ME, Schlosser P. Serum and Urine Metabolites and Kidney Function. J Am Soc Nephrol (2024). Steinbrenner I, Schultheiss UT, Bächle H, …, Schlosser P, …, Schaeffner E, Eckardt KU, Köttgen ASekula P, GCKD Ivestigators. Associations of Urine and Plasma Metabolites with Kidney Failure and Death in a CKD Cohort. Am J Kidney Dis (2024). Kellner E, Sekula P, Lipovsek J, …, Bamberg F, Büchert M, Reichardt W, Reisert M, Köttgen A. Imaging Markers Derived From MRI-Based Automated Kidney Segmentation—an Analysis of Data From the German National Cohort (NAKO Gesundheitsstudie). Dtsch Ärztebl Int (2024). Clotet-Freixas S, Zaslaver O, Kotlyar M, …, Sekula P, Steinbrenner I, Köttgen A, …, Jurisica I, Woo M, Scholey JW, Röst H, Konvalinka A. Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease. Sci Transl Med (2024). Kheirkhah A, Schachtl-Riess JF, Lamina C, Di Maio S, Koller A, …, Sekula P, …, Köttgen A, Eckardt KU, Kronenberg F. Meta-GWAS on PCSK9 concentrations reveals associations of novel loci outside the PCSK9 locus in White populations. Atherosclerosis (2023). Schlosser PScherer N, Grundner-Culemann F, Monteiro-Martins S, Haug S, …, Wuttke M, …, Köttgen M, …, Schmidts M, …, Schultheiss UT, …, Sekula P, Li Y, Köttgen A. Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine. Nat Genet (2023). Steinbrenner I, Yu Z, Jin J, Schultheiss UT, Kotsis F, …, Wuttke M, …, Chatterjee N, Sekula P, Köttgen A. A polygenic score for reduced kidney function and adverse outcomes in a cohort with chronic kidney disease. Kidney international (2022). Steinbrenner I, Sekula P, Kotsis F, von Cube M, Cheng Y, …, Eckardt KU, Schultheiss UT, GCKD investigators. Association of osteopontin with kidney function and kidney failure in chronic kidney disease patients: the GCKD study. Nephrol Dial Transplant (2022). Li Y, Cheng Y, Consolato F, Schiano G, Chong MR, …, Sekula P, Steinbrenner I, Schlosser P, …, Schultheiss UT, …, Wuttke M, …, Devuyst O, Rampoldi L, Köttgen A. Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases. JCI Insight (2022). Cheng Y, Li Y, Scherer N, Grundner-Culemann F, Lehtimäki T, …, Sekula P, Schultheiss UT; GCKD investigators. Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study. PLoS Genet (2022). Kotsis F, Schultheiss UT, Wuttke M, Schlosser P, Mielke J, …, Sekula P, Köttgen A, GCKD Investigators. Self-Reported Medication Use and Urinary Drug Metabolites in the German Chronic Kidney Disease (GCKD) Study. J Am Soc Nephrol (2021). Cheng Y, Schlosser P, Hertel J, Sekula P, Oefner PJ, …, Schmidts M; …, Thiele I, Li Y, Köttgen A. Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism. Nat Commun (2021).